24 November 2025

Calecim vs PRP: Understanding the Difference So You Can Choose What’s Right for You

Summary:
PRP uses your own platelets to stimulate repair through injections, while Calecim delivers stem cell–derived growth factors topically to “wake up” dormant follicles and improve scalp communication. Both treatments support hair growth, but your choice depends on your comfort with injections, desired consistency, and lifestyle.

Key Takeaways:

  • PRP involves injections of your own platelets; Calecim is a gentle, topical serum.

  • Calecim provides a standardised, predictable formulation; PRP results can vary depending on individual biology.

  • Calecim is non-invasive with no downtime, while PRP may involve mild discomfort and short recovery.


When it comes to hair restoration, two regenerative treatments often come up: PRP (Platelet-Rich Plasma) and Calecim Professional Hair Advanced Serum.

Both aim to improve scalp health and encourage thicker, stronger hair, but they work in very different ways. Understanding how each one works can help you choose the option that’s right for you.

Why compare Calecim hair growth serum and PRP?

When clients begin researching hair restoration, two regenerative treatments often come up — PRP (Platelet-Rich Plasma) and Calecim Professional Hair Advanced Serum.
Both are designed to encourage healthier, thicker hair by improving the scalp environment.

At Hove Hair Clinic, we offer Calecim rather than PRP, but it is important to understand both approaches so that you can make an informed decision about what feels right for you

PRP: using your body’s own platelets

PRP treatment involves drawing a small amount of your blood, spinning it in a centrifuge to concentrate the platelets, and then re-injecting that plasma into the scalp.
The platelets contain growth factors that help with tissue repair and may stimulate dormant follicles to re-enter the growth phase.

PRP in simple terms

You can think of PRP as giving your scalp a concentrated dose of its own healing potential.

Possible benefits of PRP:

  • Uses your body’s own cells, so there are no external ingredients.

  • May improve circulation and healing responses in the scalp.

  • Some small clinical studies have shown improvement in hair density and thickness, particularly in early androgenetic alopecia.

Considerations with PRP:

  • Results can vary because platelet concentration depends on your general health, hydration, and individual biology.

  • It involves injections, which may cause mild discomfort or redness for a day or two.

  • Protocols differ between clinics, which can affect consistency.

  • Results typically develop gradually over several months and may need maintenance sessions.

Calecim hair growth serum: regeneration through cellular communication

Calecim Professional is a topical serum that uses stem cell science rather than platelets.
Its patented PTT-6® complex is derived from umbilical cord lining stem cells and contains a rich mix of cytokines, growth factors and proteins that naturally calm inflammation, repair tissue and encourage new cell activity.

Calecim in simple terms

While PRP stimulates repair by releasing your own growth factors, Calecim communicates repair by introducing regenerative signals directly to the scalp.

Key benefits of Calecim:

  • Standardised formulation, ensuring consistent strength at every session.

  • Contains powerful natural messengers such as:
    • Fibroblast Growth Factors (FGFs): rebuild the skin structure and strengthen the tissue around follicles.

    • Epidermal Growth Factors (EGFs): renew scalp cells and support a balanced environment for growth.

    • Vascular Endothelial Growth Factors (VEGFs): improve microcirculation and nutrient delivery to follicles.

  • Shown in small clinical and observational studies to improve scalp conditions and visible density within 6–12 weeks.

  • Gentle enough for sensitive or reactive scalps.

Considerations with Calecim:

  • Research is emerging compared with PRP’s longer history.

  • Like all regenerative therapies, it works gradually and requires consistency.

  • Results may vary depending on the cause and stage of hair loss.

Read more to find out everything you need to know about Calecim hair growth serum.

Calecim vs PRP: at a glance

PRP (Platelet-Rich Plasma)

Calecim Professional

Main ingredient

Your own platelets and plasma

Stem cell–derived growth factors and proteins

Method

Injections or microneedling

Topical serum, applied with a 0.5mm stamp.

Comfort

Mild discomfort, short downtime

Comfortable, no downtime, can be done at home

Consistency

Varies per person

Standardised formulation

Research

Longer history, variable outcomes

Emerging evidence, strong lab and case data

Best suited for

Clients comfortable with injections and autologous methods

Clients preferring non-invasive, predictable treatment


Which is right for you?

Both treatments share one goal — to help the scalp repair and regrow healthier hair.
The right choice depends on your comfort level, lifestyle, and how you feel about the treatment process itself.

Some clients prefer the idea of using their own plasma through PRP. Others are drawn to Calecim’s gentler, science-led approach without injections or downtime.
Neither is “better” for everyone. The most important thing is choosing the method that fits your needs and values.

At Hove Hair Clinic, we guide you through that decision openly and without pressure.
If we believe Calecim can genuinely help, we will explain why.
If we feel another route may serve you better, we will tell you that too.

Our approach: transparency and trust

We believe that informed clients achieve the best outcomes.
That is why we take the time to explain how each treatment works, what the evidence shows, and what realistic results look like.

We use Mediscope imaging to track progress carefully and ensure that any improvement you see is supported by clear, measurable change.

Our goal is always the same — to restore not only hair health but also your confidence in making decisions about it.


Calecim Hair Treatment at Hove Hair Clinic

If you would like to explore whether Calecim might be right for your scalp, call 01273 711140 to book a consultation or send us your questions.
We will assess your scalp health, explain all your options, and help you choose a plan that feels right for you.

Because knowledge brings confidence, and confidence helps growth in every sense.

To knowledge, confidence and stronger strands,

Sarah
Founder, Hove Hair Clinic